Contact

Division of Chemistry,
Department of Materials Engineering Science,
Graduate School of Engineering Science,
Osaka University
1-3 Machikaneyama Toyonaka
Osaka 560-8531, Japan
Phone: +81-(0)6-6850-6228
Fax: +81-(0)6-6850-6229
E-mail: hirose#chem.es.osaka-u.ac.jp

Education

Professional Positions

Honors and Awards

Major Research Interest

Structural Organic Chemistry, Synthetic Organic Chemistry, Supramolecular Chemistry

Selected Publications

1. Young, P. G.; Hirose, K.; Tobe, Y. Axle Length Dose Not Affect Switching Dynamics in Degenerate Molecular Shuttles with Rigid Spacers. J. Am. Chem. Soc. 2014, 136, 7899-7906.

2. Hirose, K.; Miura, S.; Senda, Y.; Tobe, Y. Amplification of Enantioselectivity and Sensitivity based on Non-linear Response of Molecular Wire bearing Pseudo-18-crown-6 to Chiral Amines. Chem. Commun., 2012, 48, 6052 - 6054.

3. Hirose, K.; Yachi, Y.; Tobe, Y. Novel Chiral Recognition beyond the Limitation due to the Law of Mass Action: Highly Enantioselective Chiral Sensing based on Non-linear Response in Phase Transition Events. Chem. Commun. 2011,47, 6617-6619.

6. Hirose, K.; Ishibashi, K.; Shiba, Y.; Doi, Y.; Tobe, Y., Highly Effective and Reversible Control of Rocking Rates of Rotaxanes by Changing Size of Stimulus-Responsive Ring Components. Chem. Eur. J. 2008, 14, 5803-5811.

7. Hirose, K.; Shiba, Y.; Ishibashi, K.; Doi, Y.; Tobe, Y., An Anthracene-Based Photochromic Macrocycle as a Key Ring Component To Switch a Frequency of Threading Motion. Chem. Eur. J. 2008, 14, 981-986.

8. Hirose, K.; Nishihara, K.; Harada, N.; Nakamura, Y.; Masuda, D.; Araki, M.; Tobe, Y., Highly Selective and High-Yielding Rotaxane Synthesis via Aminolysis of Prerotaxanes Consisting of a Ring Component and a Stopper Unit. Org. Lett. 2007, 9, 2969-2972.

9. Hirose, K.; Goshima, Y.; Wakebe, T.; Tobe, Y.; Naemura, K., Supramolecular Method for the Determination of Absolute Configuration of Chiral Compounds: Theoretical Derivatization and a Demonstration for Phenolic Crown Ether - 2-Amino-1-ethanol System. Anal. Chem. 2007, 79, 6295-6302.

10. Hirose, K.; Jin, Y. Z.; Nakamura, T.; Nishioka, R.; Ueshige, T.; Tobe, Y., Chiral Stationary Phase Covalently Bound with a Chiral Pseudo-18-crown-6 Ether for Enantiomer Separation of Amino Compounds using a Normal Mobile Phase. Chirality 2005, 17, 142-148.

11. Hirose, K.; Fuji, J.; Kamada, K.; Tobe, Y.; Naemura, K., Temperature Dependent Inversion of Enantiomer Selectivity in the Complexation of Optically Active Azophenolic Crown Ethers Containing Alkyl Substituents as Chiral Barriers with Chiral Amines. J. Chem. Soc., Perkin Trans. 2 1997, 1649-1657

Selected Books and Review

1. Hirose, K. Fundamental Aspects of Host-Guest Complexation -From 1:1 to Synergistic Binding-, in Synergy in Supramolecular Chemistry, Ed. Nabeshima T., CRC Press, 2014, 261-300.

2. Hirose, K., Quantitative Analysis of Binding Properties. In Analytical Methods in Supramolecular Chemistry, Wiley-VCH Verlag, 2012, 27-66.

3. Hirose, K., Molecular Brake Systems Controlled by Light and Heat. J. Incl. Phenom. Macrocycl. Chem. 2010, 68, 1-24.

4. Hirose, K., A Practical Guide for the Determination of Binding Constants. J. Incl. Phenom. Macrocycl. Chem. 2001, 39, 193-209.